Yeast Beta Glucan Powder

Supplied Purity:  70% ; 80% purity
Quantity Provided: 1kg, 10kg, 100kg , 1000kg per month
Appearance: Light yellow to light white fine powder
Solubility: 100% water solution

Yeast Beta Glucan Powder from fungus-extract.com.png

Yeast Beta Glucan Powder is a kind of polysaccharide, which exists in the mucus secreted by some microorganisms during the growth process. It is divided into α – glucan and β – glucan. Later, Dr. diluzio of Tulun University isolated this substance from baker’s yeast and confirmed as β – glucan.

β – glucans are widely found in yeast, mushroom, oat and barley, among which β – 1,3 / 1,6 are found in yeast and mushroom glucan, while β – 1,3 / 1,4 are found in oat and barley glucan.

The main difference between β – glucan and common sugars (such as starch, hepatic sugar, dextrin, etc.) lies in the different bond connection mode. The molecular structure of common sugar is α – 1,4-glycosidic bond, while β – glucan is mainly composed of β – 1,3-glycosidic bond and contains some β – 1,6-glycosidic bond. β – glucan has a helical molecular structure due to its special bond connection and intramolecular hydrogen bond, which is easily accepted by the immune system. Therefore, when it comes to immunity, we have to mention the important role of yeast glucan.

The History of Yeast Beta Glucan Powder

In the 1940s, Dr. pillemer first discovered and reported that there was a substance in yeast cell wall that could enhance immunity. After further research by Dr. diluzio of Tulun University, it was found that the substance improving immunity in yeast cell wall was a kind of polysaccharide – β – glucan, which was isolated from baker’s yeast.

The active structure of  β – glucan is polysaccharide composed of glucose units. Most of them are bound by β – 1,3, which is the way of glucose chain connection. It can activate macrophages, neutrophils and so on, so it can increase the content of leukocyte, cytokinin and special antibody, and stimulate the immune system of the body. Then, the body is more prepared to fight microbial diseases. β – glucan can rapidly restore the ability of lymphocyte to produce cytokine (IL-1) and regulate immune function effectively. A large number of experiments have shown that β – glucan can promote the production of IgM antibody in vivo, so as to improve the humoral immunity. This kind of glucan activated cells can stimulate host non-specific defense mechanism, so its application in tumor, infectious disease and treatment of trauma has attracted much attention. β – 1,3-glucan, which is extracted by special steps and does not contain endotoxin, has been identified as a safe substance by FDA in the United States. It can be added to general foods. Many reports have shown that oral administration of yeast β – 1,3-glucan in mice can increase the phagocytosis of strong peritoneal cells. Yeast glucan is a kind of polysaccharide, β – glucan, which exists in the cell wall of yeast. β – glucan is widely distributed in various fungi and plants, such as Lentinus edodes, Ganoderma lucidum and oats. It is the main functional substance for them to play a health care role. However, yeast glucan has stronger immune enhancing activity, and has the effect of improving blood lipid, anti radiation and improving intestinal function.

In the 1970s, dextran began to be widely studied in animals and human beings. Due to the following research results, dextran supplementation has gradually become another way to enhance immune protection and reduce disease.

1. Beta Glucan supplement is not converted into glucose for absorption, but transferred into the small intestine to stimulate immunity, so it will not cause hyperglycemia. Therefore, diabetic patients can also supplement dextran to improve immunity. (effectively inhibit and prevent diabetes)

2. β – glucan has a certain viscosity and is difficult to be digested in human digestive organs, so it plays a role as dietary fiber. It can promote intestinal peristalsis, absorb harmful substances in the intestine, promote the activation of useful bacteria in the intestine, so as to improve constipation caused by insufficient food fiber intake and dyspepsia caused by gastrointestinal weakness. (regulating intestines and stomach to enhance immunity)

3. One of the functions of β – glucan is to enhance the ability of macrophages. Yeast glucan can increase the phagocytic capacity of macrophages by several times, and usually has a strong inhibition rate on mutant cells. It can protect and enhance the combat ability of immune cells, and further lock in the “residual tumor cells” of dormant period, drug resistance and subclinical lesions, and carry out targeted killing. (stimulating immune cells)

4. According to Dr. patchen of the U.S. Air Force radiobiology research center, β – glucan can effectively eliminate free radicals in vivo, thus protecting macrophages from the attack of free radicals after radiation, so that these macrophages can continue to function normally. (antioxidation)

5. When yeast glucan enters the human body, its helical structure determines that it will not be hydrolyzed into monosaccharides such as glucose in the gastrointestinal tract (therefore, β – 1, 3 and 1 are taken for diabetics, 6-glucan has no effect), but binds to specific receptors, through endocytosis (or pinocytosis), and finally enters the lymphatic system through intestinal epithelium, and from the lymphatic system into the blood system.

Gallbladder in the liver Alcohol will be converted into cholic acid, which can help digestion and lipid control. Then cholic acid will be absorbed by the small intestine back to the liver and then converted into cholesterol. As yeast glucan as dietary fiber can form a colloidal substance in the small intestine to surround the cholic acid, cholic acid can not be absorbed back to the liver through the small intestine wall, but is discharged through the digestive tract. Therefore, when the food in the intestinal tract is digested again, it needs to be digested Cholic acid, the liver can only rely on the absorption of blood cholesterol to supplement the consumption of cholic acid, thus reducing the blood cholesterol. β – glucan can absorb and excrete bile acid, promote the conversion of cholesterol to bile acid, maintain the normal metabolism of cholesterol, and effectively inhibit the increase of cholesterol in serum. (lowering blood pressure and lipid)

6. All kinds of cancer, protracted non-healing hepatitis B, recurrent oral ulcer, allergic constitution, autoimmune diseases, various infectious diseases, and even the aging process of people have a common feature: the immune response is weak or incomplete. The role of β – 1,3-D glucan can strengthen the weak or unsound immune response and return to normal. (oral administration can also stimulate immunity)

It has been clinically proved that β – 1,3-D glucan can increase skin elasticity, make skin soft and white, improve the synthesis of collagen and elastic cellulose, supply a variety of cell growth factors, eliminate wrinkles, clean skin, and repair sensitive phenomena.

The Action Mechanism of Yeast Beta Glucan Powder

When yeast beta glucan powder enters the human body, its spiral structure determines that it will not be hydrolyzed into glucose and other monosaccharides in the gastrointestinal tract. Instead, it will combine with specific receptors and enter the lymphatic system through endocytosis (or pinocytosis), and finally enter the lymphatic system through intestinal epithelium, and enter the blood system from the lymphatic system. Yeast beta glucan powder is mainly able to produce specific binding with macrophages, stimulate and activate immune factors, so as to better eliminate alien cells, prevent the invasion of foreign viruses, and then achieve the immune effect.

Differences between β – glucan and other glucans

“Ganoderma lucidum” has always been sought after as a life-saving fairy grass, known as the holy herb of reviving the dead and immortality;

Now it has been found that the magic effect of Ganoderma lucidum is due to the active component of Ganoderma lucidum polysaccharide, most of which are β – 1,3-glucan. However, Ganoderma lucidum is rich in fiber, not easy to eat, and the content is also low, and Ganoderma has a solid cell wall, it is difficult to be absorbed by the human body.

The activity of yeast glucan was much better than that of lentinan, Flammulina velutipes polysaccharide, Coriolus Versicolor Polysaccharide and konjac polysaccharide.

The only active component of β – glucan is the complex molecular structure – polysaccharide chain. They are hexagonal glucose rings connected at positions 1 and 3, and have smaller 1,6 branched chains from the main chain of 1,3 glucose. Among all kinds of β – 1,3-D glucans, only dextran with 1,6-branched chain is the most active. The dextran provided by our hospital is β – 1,3-D glucan with 1,6 branched chain, which has the strongest activity. Many studies have suggested that it is the frequency, location and length of those branched chains that interact with the immune system.

Advantages of Yeast Beta Glucan Powder

1. Source of baker’s yeast, pure natural, non transgenic, non-toxic side effects.
2. High purity, good effect and easier receptor binding.
3. The effect of β – 1,3 / 1,6 triple helix structure is more significant (yeast glucan, its main chain is β (1,3) glucan, the side chain is (1,6) glucan, this structure is different from the linear molecular structure of common sugars, but a unique triple helix structure. Its special ultramicro spiral molecular structure is the most active and easily absorbed form by human body.)
4. Adopt modern biotechnology / mild production process.
5. The quality is guaranteed by the inspection of authoritative organization.
6. Oat and barley derived β – glucans did not have the same efficacy as yeast β – glucans. At the same time, mushroom β – glucan has similar efficacy as yeast β – glucan, but the research also shows that mushroom derived β – glucan is not as efficient as yeast derived β – glucan. More Scientific research and development for yeast beta glucan powder, please check here