MIGU supplied Horny Goat Weed Extract Icariin 10% 50% 60% 98% and etc with analysis meets the EP, USP, JP, CP.....
Horny Goat Weed Extract ( Epimedium Extract ) Icariin 10% 50% 60% 98% offered by
16 years experienced cGMP manufacturer with warehosues in China
Latin Name: Epimedium sagittatum
Material Original:GanSu, China
Extracted Part: Branches and leaves
Supported Purity: Icariin 5% 10% 20% 30% 40% 50% 60% 98%
History of Epimedium (Horny Goat Weed Extract ) Icariin:
Epimedium (Horny Goat Weed) has 2,000 years to used as a sex-enhancer and Man’s Health in China.Many
cultures and clinical testing report that epimedium supports libido, erectile function,and helps to relieve menopausal
discomfort.One ingredient of it is reported to support erectile problems,for men and women with low libido,and
for women undergoing menopause. Horny Goat Weed(epimedium)is comprised of several species of epimedium,
a leafy plant which grow in the wild,most abundantly at higher altitudes like QingLing mountains in China.
Epimedium is used as an herbal aphrodisiac because it increases blood flow to the genital area. Referred
to as Yin-Yang Huo in China,where it originates,Horny Goat Weed also lowers blood pressure by dilating
capillaries and blood vessels while slowing the adrenal production that can prevent blood from reaching the
genitalia. Epimedium is grown as an ornamental herb in Asia and the Mediterranean region, and various species
are used for medicinal purposes,including Epimedium sagittatum, Epimedium brevicornum, Epimedium
wushanense, Epimedium koreanum, and Epimedium pubescens.
How does the Epimedium (Horny Goat Weed Extract) Actions in pharmacological
Epimedium herb has flavonoids such as icariin, epimedin A, epimedin B, epimedin C and baohuoside Iicariin
along with prenylated flavonol glycosides sagittasine A-C, acylated flavonol glycosides such as kaempferol
together with flavonolignans,2-phenoxychromones, a lignan,and aromatic acid derivatives.Some of these be of
compounds, particularly icariin ,promote endothelial nitric oxide-dependent relaxation of blood vessels and
hence can help for the treatment of erectile function and impotence.
Therapeutic effects of Horny Goat Weed include invigorating kidney function, reversing male and female
infertility, strengthen tendons and bones, decreasing muscular spasm, relieving coughs and lowering blood
pressure. The herb has also been used for liver and kidney toning and has improved the life of chronic renal
failure patients in a Chinese study.
Horny Goat Weed Extract Specification Supplied
MIGU owned independent workshop which mainly produce the icariin ingredients for epimedium
extract. All of the material getthering from GanSu province with wild material. We owned experience extracting
engineers for guarantee our high quality ingredients of icarrin. Now listed some of welcomed ingredients
as below for your reference. If you have any other customizing required, please email us freely.
Indications and Uses of Horny Goat Weed Extract Icariin
Horny goat weed is used for weak back and knees .joint pain.osteoarthritis,mental and physical fatigue,memory
loss.high blood pressure,heart disease,bronchitis,liver disease, HIV/AIDS,polio,a blood disorder called chronic
leucopenia, viral infections of the heart, bone loss after menopause, weak bones (osteoporosis), and as a tonic
Some men use horny goat weed for sexual performance problems including erectile dysfunction (ED) and
involuntary ejaculation. It is also used to arouse sexual desire
How does it work for Horny Goat Weed Extract
Horny goat weed contains chemicals which might help increase blood flow and improve sexual function. It also
contains phytoestrogens, chemicals that act somewhat like the female hormone estrogen, that might reduce
bone loss in postmenopausal women.
A : Function of Erectile Dysfunction
Study show: Oral treatment with icariin (>98.6% purity ) for 4 weeks potentially improves erectile function .This
effect is correlated with an increase in PSM and the expression of certain NOS in the CC of castrated rats.These
results suggest that icariin may have a therapeutic effect on erectile dysfunction(Asian J Androl 2005 Dec;7:381
-388)
B:Male Sexual Enhancement
Growing body of research shows that isolated Icariin inhibits the enzyme phosphodiesterase-5(PDE-5) and
significantly increase nitric oxide synthase,helping to improve erectile function in multiple model.Studies also
indicate that isolated Icariin increase circulating testoserone levels . However, unlike prescription medications
epimedium doesn’t work in an hour or two.It normally takes several days for the sexual benefits to be noticed
C:Immune Enhancement
Studies suggest that isolated Icariin plays role in immune enhancement via the regulation of various hormone
pathways.Specifically,research indicates estrogenictype activity in female breast cell lines, inhibiting property
in male prostate cell lines ,as well as testosterone mimetic properties
D:Anti-Depressant,Antioxidant
Recent finding point to animportant role for isolated Icariin in the mitigation of symptoms associated with
depression . In particular, isolated Icariin has been shown to reduce know stress -induced triggers,such as brain
monoamine oxidase A&B, serum corticotropin -releasing factor, and cortisol. Studies show that, from a kinetic
standpoint , isolated Icarrin is a far more effective antioxidant than know antioxidants such as vitamins E and C
Most important,however, isolated Icariin is demonstrated to significantly increase naturally -occuriing levels of
super antioxidant,SOD( superoxide sismutase).
Scientific Study of Horny Goat Weed Extract
Human studies
As 2014, we could only find one human study with epimedium herb. Effect of Epimedium sagittatum on quality
of life and cellular immunity in patients of hemodialysis maintenanceZhongguo ZhongXiYi Jie He Za Zhi.1995.In
present study, we investigated the therapeutic effect of Epimedium Sagittatum on patients of hemodialysis
maintenance.22 cases of regular hemodialytic patients were treated with this herb in the form of decoction.12
patients with hemodialysis were served as controls.It was found that Epimedium plant had sexual potentiation
effect and improved the quality of life in the patients of chronic renal failure with regular hemodialysis
Interleukin 2 (I-L2) activity of peripheral blood monocytes stimulated by PHA was increased significantly in the
patients treated with the herbal preparation.It is suggested that this Chinese medicine had therapeutic effect
on sexual disorder & immunologic inadequacy in the patients of chronic renal failure undergoing hemodialysis
Drug interactions
It is possible that epimedium could interact with prescription stimulant drugs, anti-depressants Zoloft, Paxil,
Prozac, heart medications blood pressure medications,and erectile dysfunction meds such as Viagra,Cialis,and
Levitra. Caution is advised when mixing herbal remedies with prescription medications.
Animal studies
OsteoporosisPrevention of bone loss by aqueou extract of Epimedii sagittatum in an ovariectomized rat model
of osteoporosis.ZhongXiYiJieHeXueBao.2006; Department of Pharmacy,Yueyang Hospital of Chinese Integrative
Medicine,Shanghai University of TraditionalChinese Medicine,Shanghai,China.Our findings assessed on the basis
of biochemical test, bone mineral density and histomorphometric parameters show that aqueous extract of
Epimedii sagittatum has a definite antiosteoporotic effect and can prevent the ovariectomy-induced bone loss
in rats.
In vitro studies
An in vitro study means that the evaluation was done in a lab not using any animals or humans.
Effect on cartilage
Effect of five species of Epimedium on growth of cartilage and proliferation of cartilage cell in vitro
Zhongguo Zhong Yao Za Zhi. 2006.
To observe the effect of Epimedium brevicornum plant, E. sagittatum, E. koreanum, E, wushanense and E.
elongntum on the growth of cartilage and proliferation of cartilage cell in vitro.E.brevicornum and E.sagittatum
can improve the growth of cartilage and proliferation of cartilage cell in vitro.The other three Epimedium
species did not have the same effect.
Osteoporosis and bone health
Effects of rat serum containing total flavonoid extract of Epimedium sagittatum on development of osteoblasts
Zhongguo Zhong Yao Za Zhi. 2008; Department of Pharmacy, Lanzhou General Hospital, PLA, Lanzhou, China.
To investigate the effects of total flavonoid extract of Epimedium sagittatum on the proliferation and
differentiation of newborn rat calvarial osteoblasts.Flavonoids from this herb have anti-osteoporosis properties
The flavonoid icariin may be largely responsible for these benefits.
Safety
It is interesting to note that although at least 15 fifteen active compounds have been identified in epimedium
extracts,(luteolin, icariin,quercetin,and various epimedins),many supplement companies currently use alcohol
extracts standardized only for high levels of icariin.The traditional use of epimedium,however,is as a hot-water
decoction(tea),which would result in a very different profile of active constituents when compared to the high
icariin alcohol extracts that are more commonly used in commercial products. Although at least one test test
tube study has shown icariin to protect liver cells from damage with by various toxic compounds,other feeding
studies ( in rodents ) have suggested that high-dose icariin may be associated with kidney and liver toxicity
There have been no reports of adverse side effects associated with the traditional preparation of epimedium
(water-extracted) at the suggested dosage (250 to 1,000mg per day).
The Dosage of Horny Goat Weed Extract
Because all of the existing scientific evidence for the anti-stress and cortisol-controlling effect of epimedium
has been demonstrated for water-extracted epimedium (that is, as a tea), and because this form of extraction
may result in a safer form of epimedium ( compared to the high-icariin alcohol extract ), it may be prudent to
select supplements that specifically use a more traditional formulation. There have been no reports of adverse
side effects associated with the traditional preparation of epimedium ( water-extract) at the suggested dosage
(250-1,000mg/day in 2-3 divided doses).