Griffonia Seed Extract

Original:Griffonia simplicifolia,Ghana

Supplied Purity: 10%~ 98%
Appearance: yellow brown or white to off white powder
Production Capacity: 1000kg per month
Pacakge: 1)1kg/bag(1kg net weight,1.2kg gross weight, packed in an aluminum foil bag outside;double-layer PE inside).2)25kg/drum  (25kg net weight , 28kg gross weight ;Packad in a cardboard-drum.

About for the Griffonia Seed Extract

African Griffonia Seed belongs to the shrub plant of the legume family, Caesalpinioideae subfamily, and Ghanese Seed genus, originating from West African countries such as Ghana, Ivory Coast, Côte d’Ivoire, and Togo. In West Africa,Griffonia Seed has a long history of folk medicine use. Its leaves and leaf juice can be used to treat external injuries and diseases related to the bladder and kidneys, respectively; in addition, Griffonia Seed can also be used to treat diarrhea, vomiting, and stomach pain; and its most widely known properties are its antibacterial and aphrodisiac properties. Recent studies have found that the main active ingredient in Griffonia Seed extract is 5-hydroxytryptophan (5-HTP). 5-HTP is an amino acid substance and a precursor of the inhibitory neurotransmitter serotonin, which can increase brain 5-HT concentration, inhibit depression, promote melatonin synthesis, and improve sleep quality.

However, the distribution range of 5-HTP is narrow, and it has only been found to be abundant in Griffonia seeds. Given its good activity, 5-HTP has been sold as a dietary supplement in the United States, the United Kingdom, and Canada in recent years; the demand for such drugs in China is also increasing. Due to the limited resources of Griffonia seeds in Africa, coupled with the increasing costs of large-scale collection and logistics, the production cost of 5-HTP remains high. In order to better utilize this plant germplasm resource sustainably, it is particularly important to introduce and domesticate this species in tropical and subtropical regions of China.

Efficacy and function of Griffonia Seed Extract

5-HTP is a natural amino acid extracted from the dried seeds of the legume shrub plant, Crotalaria juncea. Its chemical name is 5-hydroxy-3-indolyl-α-aminopropionic acid.Compared to synthetic 5-hydroxytryptophan, its use is safer.People with low serotonin (5-HTP) levels are more prone to depression, impulsivity, and even violent aggressive behaviors. 5-hydroxytryptophan can be converted into 5-HTP through decarboxylation in the body, which can help the body increase 5-HTP levels and is an important neuropharmacological drug.
Modern research has found that 5-hydroxytryptophan has:Physiological effects such as antidepressant, central analgesic, sleep improvement, anti-stress, and endocrine regulation.

What is the use of Griffonia Seed Extract?
1. Improve depressive mood
Through experimental observation of the utilization of TRP (tryptophan) in depressed individuals, it was found that the L-TRP utilization in patients with severe depression was significantly lower than that in patients with mild depression.
2. Central analgesic effect
TRP may exert a central analgesic effect by increasing the content of serotonin (5-HTP) in the central nervous system.After descending fibers of 5-HTP in the brain reach the spinal cord, they can be mediated by interneurons to activate enkephalin neurons in the posterior horn glia region.The latter can inhibit the transmission of peripheral pain information to secondary neurons through presynaptic inhibition, thereby exerting a central analgesic effect.
3. Impact on the cardiovascular system
Research on different hypertensive animal models in rats has shown that TRP also exhibits antihypertensive activity.
4. Improve sleep quality
5-Hydroxytryptophan can generate the precursor of neurohormone serotonin in the body with the help of vitamin B6, thereby promoting sleep and mental stability.
5. Physiological effects of anti-stress
The study found that injecting 5-hydroxytryptophan can reduce the mutual aggression of mice in a short period of time, and the degree of reduction is proportional to the amount of 5-hydroxytryptophan injected.
6. It has an impact on neuroendocrinology
5-Hydroxytryptophan can be converted into certain hormones to directly participate in endocrine activities, and it can also be converted into the central neurotransmitter 5-hydroxytryptamine to indirectly affect the release of neurohormones.
7. Suppress appetite
Animal experiments have also found that 5-HTP can increase the blood concentration of leptin, enhance appetite control, and prevent overeating.

Clinical research has found that taking 8 milligrams (mg) of 5-HTP per kilogram of body weight per day for five weeks, without the support of a dietary prescription, resulted in an average weight loss of 5%
What kind of people are suitable for supplementing with Griffonia Seed Extract?
– Emotionally unstable individuals
– People with high work and life stress
– People who have difficulty falling asleep and sleeping well due to shallow sleep
– People who need to regulate their appetite to lose weight
– Population with menopausal syndrome
– People with endocrine disorders

MIGU also provide other botanical extract any interesting for it, please email us freely. More Scientific research and development for Griffonia Seed Extract , please check here