New discovery of Ganoderma lucidum polysaccharide
Ganoderma lucidum polysaccharides from more than 3000 existing pharmaceutical ingredients and water extracts of traditional Chinese medicine stand out. It has been confirmed by scientists that Ganoderma lucidum polysaccharides can inhibit new coronavirus in infected animals. Cool! But I think it’s even cooler that Ganoderma lucidum polysaccharide is the only one of the five potential stocks that has been proved to be “effective” in the end. It can be eaten as a meal (not as a medicine) and a daily health food.
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Since novel coronavirus pneumonia (COVID-19) has been broken out, Ganoderma lucidum has been found to be a good theoretical basis for the disease resistance. Now, the report published in february2021 by the team led by the center for genomic research of the Central Academy of Sciences (PNAs) provides direct evidence for Ganoderma lucidum to inhibit SARS cov-2.
The researchers first infected hamsters with new crown virus, and then orally administered the polysaccharide extract with immunoregulatory activity the next day, at a dose of 200 mg/kg per day. After three consecutive days of treatment, the virus amount in hamster lungs was about half of the control group without any drugs (see figure below).
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Since the weight of hamsters did not decrease significantly, the researchers believe that Ganoderma lucidum polysaccharide extract can effectively inhibit the proliferation of neocoronavirus in the lung without the doubt of food safety and on the premise of taking it immediately after infection.
Although this is “only” the experimental result of hamster, the above experimental result has its reference value because the respiratory tract tissue of hamster is similar to that of human. When the immune system is stimulated by infection, it also produces cytokines (protein molecules that transmit information between cells and regulate immune response) similar to that of human.
It is worth mentioning that this study is not only about Ganoderma lucidum. The aim of the researchers is to screen out the ingredients that can inhibit the infection of NCV. Therefore, seven “potential stocks” including the Ganoderma lucidum extract powder — Ganoderma lucidum polysaccharides were selected from more than 3000 existing drugs and water extracts of traditional Chinese medicine through two rounds of in vitro cell experiments to comprehensively evaluate their safety and effectiveness.
The effectiveness of Ganoderma lucidum polysaccharide extract in inhibiting virus replication in vitro is far from that of single component western medicine. However, when it enters the body through the gastrointestinal tract, it can effectively suppress virus breeding in the lung, even better than some western medicine with beautiful cell experimental data.
Such a contradictory result is nothing more than a reminder to us that whether it is experimental animals or even human beings, they are not using a single cell, but a whole set of systems composed of a variety of cells to fight the virus. Therefore, the brilliant performance of Ganoderma lucidum polysaccharide in vivo must be related to its enhancement of the antiviral ability of the whole system (including the immune system). Two Western medicines (mefloquine and neflinavir) used in animal experiments were more effective than Ganoderma lucidum polysaccharide extract in inhibiting neocoronavirus in vivo, but they were used for treatment after all, not for eating as soon as they wanted, let alone for preventing infection.
For the other two Chinese herbal medicines, Perilla frutescens and Mentha haplocalyx, the experiment is to extract 1 gram of Chinese herbal medicine in 20 ml of water for 4 hours. In animal experiments, hamsters need to eat 200 mg of water extract per kilogram of body weight every day to convert it into a dose for adults. How many herbs should be prepared for one person per day? Not to mention if you share it with your family and friends. Even if you have the patience to cook a lot of herbs every day, how can you ensure the source stability of each batch of herbs and maintain the consistency of its active ingredients in the process of preservation?It is better to eat Ganoderma lucidum health food which has obtained immunity efficacy certification faster!
In fact, the components of Ganoderma lucidum that help to prevent virus are not only active polysaccharides. Like the ganoderma lucidum spore oil & ganoderma lucidum spore oil softgel which used high tech super critical CO2 extract from ganoderma lucidum spore powder with high triterpene contents. With the ingredients of Ganoderma lucidum, protect themselves and protect their families, can you achieve the goal of family health?(More Scientific research and development for the New discovery of Ganoderma lucidum polysaccharide , please check here)
Reference: Jia-Tsrong Jan, et al. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection.https://www.pnas.org/content/118/5/e2021579118.long Proc Natl Acad Sci U S A. 2021; 118(5): e2021579118. doi: 10.1073/pnas.2021579118.
