Ganoderma inhibit the growth of gastric tumor
The biggest difference between Ganoderma lucidum and medicine and many other health foods is that Ganoderma lucidum is effective for the ancestors, and it is effective for the general public to eat it since ancient times. Scientists can only use animal and cell experiments to understand why it works; instead of finding out the possibility of Ganoderma lucidum in cell and animal experiments, we can invite the public to buy a good mind and hope.
The same is true of Ganoderma lucidum Extract Powder in the field of anti-tumor. Therefore, the research on Ganoderma lucidum anti-tumor can only be improved in the world for more than 50 years since the first research report on the anti-tumor of Ganoderma lucidum published by the National Cancer Center of Japan in 1986.
How to study Ganoderma lucidum in vivo to fight lung cancer, liver cancer, colon cancer and breast cancer, we must see a lot, but you can know that Ganoderma lucidum can also fight gastric cancer?!
In October 2019, the ethanol extract (GLE) rich in triterpene like ganoderma lucidum spore oil is proved to inhibit the growth of gastric tumor in vivo by an associate professor Hyo Jeng Kang, associate professor of the school of medicine of national Qingbei University of Korea, published in molecules (molecular Journal).
Effect of Ganoderma lucidum dose
The researchers implanted human gastric cancer cell line on the back of mice with immunocompromised function (nude mice), and then gave mice oral Ganoderma lucidum ethanol extract gle at a dose of 30 mg/kg per day after two weeks of tumor growth.
When the experiment was carried out on day 23, the growth rate of the tumor in the Ganoderma lucidum group (Figure 1 green curve) was significantly slower than that of the control group (Figure 1 black curve) that did not receive any treatment.
However, if the oral administration of GL in tumor mice was reduced to one third and only 10 mg / kg per day, the tumor growth rate of the Ganoderma lucidum group (green curve in Figure 2) was comparable to that of the untreated control group (black curve in Figure 2). In other words, Ganoderma lucidum ethanol extract after digestion and absorption in the gastrointestinal tract, can indeed play a role in inhibiting gastric cancer in the body with insufficient immunity, but this role is based on the premise that the dose must be sufficient; once the dose is insufficient, it may become a “Ganoderma lucidum invalid” frustration outcome.
The effect of one plus one is not necessarily greater than that of two
The synergistic effect of quercetin (QCT) and Ganoderma lucidum extract powder on gastric cancer was also discussed.
The antioxidant activity of quercetin provides a part of scientific basis for “full intake of vegetables and fruits can reduce the risk of cancer”. Therefore, when it is combined with Ganoderma lucidum, it should be able to play a role of one plus one greater than two, right?
If you are willing to go back to the animal experiment results shown in Figure 1 and Figure 2, it is not difficult to find that:
High dose (30 mg / kg each) of “Ganoderma lucidum + quercetin” is not better than separate use of the two, while low dose (10 mg / kg each) of “Ganoderma lucidum + quercetin” is better than single use of low dose of Ganoderma lucidum or single use of low dose of quercetin, but the good effect is no different from single use of high dose of Ganoderma lucidum.
That is to say, from the perspective of human nature, we always want to “add East and west” to improve the anti-cancer effect of Ganoderma lucidum. However, from the scientific results, it may be better to “eat enough Ganoderma lucidum” and match it with the appropriate daily diet, which can help our own body to develop a good anti-cancer self-healing ability.
Ganoderma inhibit the growth of gastric tumor. jpg
Epstein Barr virus can coexist peacefully or induce canceration
It is worth mentioning that the human gastric cancer cell line mkn1-ebv used in the above animal experiments is a kind of gastric cancer cell with Epstein Barr virus (EBV). About 10% of gastric cancer patients belong to this kind of EB virus associated gastric cancer, which can be detected in cancer tissues.
In fact, the vast majority of adults have been infected with Epstein Barr virus and do not know it, because when it invades the B cells in the mucosal tissue through the oral mucosa (saliva), it will be dormant in the B cells in the state of eye rest, and live peacefully with the infected person for a lifetime.
Only a few people will suffer from gastric cancer, nasopharyngeal carcinoma or lymphoid cancer because of EB virus, and the immune function is not good enough, which is the key to break the balance and induce cancer.
Therefore, human beings should learn how many viruses can coexist peacefully! The simplest way to make peace with these invaders at the same time is to use Ganoderma lucidum for maintenance, because Ganoderma lucidum contains polysaccharides that can regulate immunity and triterpenoids that can inhibit virus proliferation.
When cancer happens, we should eat Ganoderma lucidum well, because it not only needs polysaccharides to enhance the immune system’s ability to fight against cancer cells, but also needs triterpenoids to fight against cancer cells directly.
The above-mentioned Korean studies have proved that the ethanol extract of Ganoderma lucidum rich in triterpenoids can inhibit the growth of EB virus related gastric cancer in vivo precisely because it can stimulate the virus in cancer cells to disintegrate cancer cells without causing damage to normal cells. Ganoderic acid A (ganoderic acid a) in the triterpenoids of Ganoderma lucidum is the main component of “fighting poison with poison”.
While Ganoderma lucidum triterpenoids such as Ganoderma lucidum acid a go to the front line to kill the enemy, can’t Ganoderma lucidum polysaccharides take good care of the rear through the immune system to fight a beautiful victory?
Therefore, different ingredients can be taken out and discussed separately, but in fact, when eating Ganoderma lucidum, please be sure to choose the Ganoderma Lucidum with complete ingredients, taking into account both the front and the rear, so as to have the expected effect. We think the ganoderma lucidum spore oil softgel is the best chooice. More Scientific research and development for Ganoderma inhibit the growth of gastric tumor , please check here
Reference:
Sora Huh , et al. Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts. Molecules. 2019 Oct 24; 24(21): 3834. doi: 10.3390/molecules24213834.(https://www.mdpi.com/1420-3049/24/21/3834)
